interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAAATGGAAGTGGG)
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=1.54, R-factor=0.166)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
multimeric complexes8ek8_EF
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQKRARN

Estimated binding specificities ?

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# IC=2.962 IC/col=0.741 n_of_columns=4 specificity:   
A |  15   0   6  81
C |  15   0   6   7
G |  15  96  78   4
T |  51   0   6   4
scan!

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updated Fri Sep 13 10:45:11 2024