interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAAATGGAATGGGG)
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=1.52, R-factor=0.159)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQKRARN

Estimated binding specificities ?

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# IC=3.039 IC/col=0.217 n_of_columns=14 specificity:   
A |  24  24  24  24  24  23   4   6   0  49  22  24  24  24
C |  24  24  24  24  24  21   4  78  96  17  22  24  24  24
G |  24  24  24  24  24  21   4   6   0  15  25  24  24  24
T |  24  24  24  24  24  31  84   6   0  15  27  24  24  24
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updated Tue Dec 19 03:08:52 2023