interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAAATGGAATGGGG)
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=1.52, R-factor=0.159)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
multimeric complexes8ek8_EF
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQKRARN

Estimated binding specificities ?

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# IC=4.007 IC/col=0.801 n_of_columns=5 specificity:   
A |   9   9   0   0  67
C |  11   9  96  96   9
G |   9   9   0   0  11
T |  67  69   0   0   9
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updated Fri Sep 13 10:45:16 2024