8ekv_F : 3D-footprint complex

structure name	HUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAAGCGGATGTGGG) (Transcription factor PU.1)
reference	Terrell et al. 'Cell 42 112671 2023
source	Homo sapiens
experiment	X-ray (resolution=1.62, R-factor=0.167)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Etsdomain;
reference complex	8ee9_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8ekv_F interface=58,59,62,65,66, kirlyqflldllrsgdmkdsiwwvdkdkgtfqfsskhkealahrwgiqkgnrkkmtyQKmaRalRNygktgevkkvkkkltyqfsgevlgr
interface signature	QKRRN

Estimated binding specificities ?

contact

# IC=3.500 IC/col=0.250 n_of_columns=14

specificity:

A |  24  24  24  24   7   0   2  74  24  22  24  24  24  24
C |  24  24  24  24  74   0   2   8  24  22  24  24  24  24
G |  24  24  24  24   7  96  88   7  24  30  24  24  24  24
T |  24  24  24  24   8   0   4   7  24  22  24  24  24  24

scan!

home
updated Tue Dec 19 03:08:56 2023