interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAAGCGGATGTGGG)
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=1.62, R-factor=0.167)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
multimeric complexes8ek8_EF
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQKRRN

Estimated binding specificities ?

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# IC=3.490 IC/col=0.872 n_of_columns=4 specificity:   
A |   7   0   2  74
C |  74   0   2   8
G |   7  96  88   7
T |   8   0   4   7
scan!

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updated Sat Aug 2 23:57:22 2025