interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAAGGAGAAGTAGG)
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=1.42, R-factor=0.154)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
multimeric complexes8ek8_EF
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRARN

Estimated binding specificities ?

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# IC=3.059 IC/col=0.765 n_of_columns=4 specificity:   
A |  10  96   6  78
C |  10   0   6   6
G |  63   0  78   6
T |  13   0   6   6
scan!

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updated Sat Aug 2 23:57:27 2025