8ekz_F : 3D-footprint complex

structure name	HUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAAGGAGAAGTAGG) (Transcription factor PU.1)
reference	Terrell et al. 'Cell 42 112671 2023
source	Homo sapiens
experiment	X-ray (resolution=1.42, R-factor=0.154)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Etsdomain;
reference complex	8ee9_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8ekz_F interface=59,62,63,65,66, kirlyqflldllrsgdmkdsiwwvdkdkgtfqfsskhkealahrwgiqkgnrkkmtyqKmaRAlRNygktgevkkvkkkltyqfsgevlg
interface signature	KRARN

Estimated binding specificities ?

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# IC=3.100 IC/col=0.221 n_of_columns=14

specificity:

A |  24  24  24  24  22  20   6   6   0  10  24  24  24  24
C |  24  24  24  24  27  20   6  78   0  63  24  24  24  24
G |  24  24  24  24  25  20   6   6   0  10  24  24  24  24
T |  24  24  24  24  22  36  78   6  96  13  24  24  24  24

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updated Tue Dec 19 03:09:00 2023