interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAGGAGAAGTAGGG)
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=2.34, R-factor=0.227)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
multimeric complexes8ek8_EF
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRARN

Estimated binding specificities ?

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# IC=3.296 IC/col=0.824 n_of_columns=4 specificity:   
A |   4   3   0  12
C |   4  85   0  60
G |   7   3   0  12
T |  81   5  96  12
scan!

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updated Fri Sep 13 10:45:31 2024