interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAGGAGAAGTAGGG)
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=2.34, R-factor=0.227)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRARN

Estimated binding specificities ?

contactlogo
# IC=3.347 IC/col=0.239 n_of_columns=14 specificity:   
A |  24  24  24  12  96   5  81  36  23  24  24  24  24  24
C |  24  24  24  12   0   3   4  20  21  24  24  24  24  24
G |  24  24  24  60   0  85   7  20  31  24  24  24  24  24
T |  24  24  24  12   0   3   4  20  21  24  24  24  24  24
scan!

home
updated Tue Dec 19 03:09:05 2023