interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAACCGGAAGTGGG)
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=1.45, R-factor=0.152)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQKRARN

Estimated binding specificities ?

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# IC=4.033 IC/col=0.288 n_of_columns=14 specificity:   
A |  24  24  24  24  22  21   4   6   0   1  24  24  24  24
C |  24  24  24  24  27  21   4  78  96   1  24  24  24  24
G |  24  24  24  24  25  21   4   6   0  92  24  24  24  24
T |  24  24  24  24  22  33  84   6   0   2  24  24  24  24
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updated Tue Dec 19 03:10:56 2023