interface graph thumbnail
legend  pdf

structure nameHUMAN PU.1 ETS-DOMAIN (165-270) BOUND TO D(AATAACCGGAAGTGGG)
(Transcription factor PU.1)
referenceTerrell et al. 'Cell 42 112671 2023
sourceHomo sapiens
experimentX-ray (resolution=1.45, R-factor=0.152)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
multimeric complexes8ek8_EF
reference complex8ee9_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQKRARN

Estimated binding specificities ?

readout + contactlogo
# IC=5.498 IC/col=0.916 n_of_columns=6 specificity:   
A |  10  10   0   0   0   0
C |  10  10  96  96   0  11
G |  10  10   0   0  86  85
T |  66  66   0   0  10   0
scan!

home
updated Sat Aug 2 23:59:52 2025