interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE MADS-BOX/MEF2 DOMAIN OF MEF2D BOUND TO DSDNA AND HDAC4 DEACETYLASE BINDING MOTIF
referenceChinellato et al. J.Mol.Biol. 436 168541 2024
sourceHomo sapiens
experimentX-ray (resolution=2.40, R-factor=?)
structural superfamilySRF-like;
reference complex8q9n_B 8q9p_B 8q9q_A 8q9r_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRK/RVK

Estimated binding specificities ?

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# IC=5.379 IC/col=0.538 n_of_columns=10 specificity:   
A |   0   0  69  24  24  24  24   9  96  69
C |  96   0   9  24  24  24  24  11   0   9
G |   0   0   9  24  24  24  24   9   0   9
T |   0  96   9  24  24  24  24  67   0   9
scan!

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updated Fri Aug 1 15:00:59 2025