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3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.


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updated Fri Sep 13 13:20:30 2024
structure nameSTRUCTURE OF HUMAN POT1 DNA BINDING DOMAIN BOUND TO A 5'- PHOSPHORYLATED JUNCTION OF A TELOMERIC DNA HAIRPIN WITH A 3'- OVERHANG
(Protection of telomeres protein 1)
referenceNandakumar et al. Science 381 771 2023
sourceHomo sapiens
experimentX-ray (resolution=2.16, R-factor=0.182)
structural superfamilyNucleic acid-binding proteins;
sequence familyTelomerebinding protein alpha subunit, cen;
reference complex3kjp_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence