3kjp_A : 3D-footprint complex

3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

Dendrogram of similar interfaces ?

matrix format

structure name	CRYSTAL STRUCTURE OF HPOT1V2-GGTTAGGGTTAG (Protection of telomeres protein 1)
reference	Nandakumar et al. Proc.Natl.Acad.Sci.USA 107 651 2010
source	Homo sapiens
experiment	X-ray (resolution=1.80, R-factor=?)
structural superfamily	Nucleic acid-binding proteins;
sequence family	Telomerebinding protein alpha subunit, cen;
redundant complexes	8sh0_A 8sh1_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3kjp_A interface=25,26,33,36,37,43,53,55,57,82,84,89,91,155,217,218,237,239,260,265,267, atnyiytplnqlkggtivnvygvvKFfkppylSkgTDycsvvTivdqtnvklTcLlFsgnyealpiiykngdivrfhrlkiQvYkketQgItssgfasltfegtlgapiiprtsskyfnfttedhkmvealrvwasthmspstllklcdvqpmqYfdltcqllgkaevdgasfllkvwdgtrtpfpswrvliqdlvlegdlshihrlqnltidilvYDnhvhvarslkvgsflriySlHtklqsmnsenqtmlslefhlHggtsYgRgirvlpesnsdvdqlkkdlesanlta

  
  KGFGST--TTDTTGTGLAFA----QGYGQGIA--------YT----------------------------YGDG--------ST--HT------------HT--YTRT   L                            +-----3kjp_A    
                                                                                                                            +-----------------1 
  KGFGST--TTDTTGTGLAFT----QGYGQGIA--------YT----------------------------YGDG----------ST--HT----------HG--YTRT   L       +--2                 +-----7qxs_P    
                                                                                                                         !  ! 
  ----STTT--DT--QCHCFTKTTGRCYCQCLGKGDG------------------------------------------------------------------------   L     +-3  +-----------------------7cuh_A    
                                                                                                                       ! ! 
  ------------------------------------EGTGYG--SGDGKGATFTSGVGNGYTLGYG--KGYT--------------------------KT------RT   L   +-4 +--------------------------1s40_A    
                                                                                                                     ! ! 
  ----------------------------------------KTNT----------------------WTRT----RTITYTET--------RTWTYTTT----NT----   L --5 +----------------------------6irq_A    
                                                                                                                     ! 
  ------------------------------------------------------------------FTNT--------------------------------------   L   +----------------------------6bhx_B

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updated Fri Sep 13 17:20:21 2024