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structure nameZNFS 3-11 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 35MER DNA 35- 20
(Transcriptional repressor CTCF)
referenceHorton et al. 'Nucleic 51 8447 2023
sourceHomo sapiens
experimentX-ray (resolution=3.14, R-factor=0.251)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex8ssq_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureERYEKRYKRQTRSDVQRHMQQLR

Estimated binding specificities ?

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# IC=23.208 IC/col=0.774 n_of_columns=30 specificity:   
A |   3   0   0  68   3   0  68   0  24  24  24  24  24  24  24  24  24  24   0  80   4   0  96   0   0   0   0   0   0   0
C |   4   0  93   9   6   0   9  96  71  24  24  24  24  24  24  24  24  24  96   4   3  96   0   0   0   0   0   0  96   0
G |   6  96   0   9  19   0   7   0   0  24  24  24  24  24  24  24  24  24   0   3  86   0   0  96  96   0  96  96   0  96
T |  83   0   3  10  68  96  12   0   1  24  24  24  24  24  24  24  24  24   0   9   3   0   0   0   0  96   0   0   0   0
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updated Tue Dec 17 19:47:50 2024