8ssr_A : 3D-footprint complex

structure name	ZNFS 3-11 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 35MER DNA 35- 20 (Transcriptional repressor CTCF)
reference	Horton et al. 'Nucleic 51 8447 2023
source	Homo sapiens
experiment	X-ray (resolution=3.14, R-factor=0.251)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
reference complex	8ssq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8ssr_A interface=18,21,25,44,47,50,74,75,78,100,103,130,132,133,136,188,190,191,194,216,218,219,248, trphkcpdcdmafvtsgElvRhrrYkhthekpfkcsmcdyasvEvsKlkRhirshtgerpfqcslcsyasrdtYKlkRhmrthsgekpyecyicharftQsgTmkmhilqkhtenvakfhcphcdtviaRkSDlgVhlrkqhsyieqgkkcrycdavfheryaliqhqkshknekrfkcdqcdyacrQeRHmiMhkrthtgekpyacshcdktfrQkQLldmhfkryhdpnfvpaafvcskcgktftRrntmarhadnca
interface signature	ERYEKRYKRQTRSDVQRHMQQLR

Estimated binding specificities ?

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# IC=24.447 IC/col=0.815 n_of_columns=30

specificity:

A |   0   0   0   0  96   0   0   0   0   1  17   0   7  24  24  24  24  24  24  24  24   0   0   7  96  60   7   1   0  91
C |  96   0  96  96   0  96  96   0   0  90   3   0   7  24  24  24  24  24  24  24  24   0   0   7   0  28   7   0  96   1
G |   0  96   0   0   0   0   0   0  96   4   0  96  63  24  24  24  24  24  24  24  24  84  96  11   0   5   7  94   0   1
T |   0   0   0   0   0   0   0  96   0   1  76   0  19  24  24  24  24  24  24  24  24  12   0  71   0   3  75   1   0   3

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updated Sun Aug 3 03:11:52 2025