8ssr_A : 3D-footprint complex

structure name	ZNFS 3-11 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 35MER DNA 35- 20 (Transcriptional repressor CTCF)
reference	Horton et al. 'Nucleic 51 8447 2023
source	Homo sapiens
experiment	X-ray (resolution=3.14, R-factor=0.251)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
multimeric complexes	7w1m_ABDEH
reference complex	7w1m_H
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8ssr_A interface=18,21,25,44,47,50,74,75,78,100,103,130,132,133,136,188,190,191,194,216,218,219,248, trphkcpdcdmafvtsgElvRhrrYkhthekpfkcsmcdyasvEvsKlkRhirshtgerpfqcslcsyasrdtYKlkRhmrthsgekpyecyicharftQsgTmkmhilqkhtenvakfhcphcdtviaRkSDlgVhlrkqhsyieqgkkcrycdavfheryaliqhqkshknekrfkcdqcdyacrQeRHmiMhkrthtgekpyacshcdktfrQkQLldmhfkryhdpnfvpaafvcskcgktftRrntmarhadnca
interface signature	ERYEKRYKRQTRSDVQRHMQQLR

Estimated binding specificities ?

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# IC=23.474 IC/col=0.782 n_of_columns=30

specificity:

A |   2   0   0  72   2   0  55   0  27  24  24  24  24  24  24  24  24  24   0  82   2   0  96   0   0   0   0   0   0   0
C |   7   0  94   7  10   0   9  96  69  24  24  24  24  24  24  24  24  24  96   2   4  96   0   0   0   0   0   0  96   0
G |   2  96   0  10   9   0  15   0   0  24  24  24  24  24  24  24  24  24   0   2  88   0   0  96  96   0  96  96   0  96
T |  85   0   2   7  75  96  17   0   0  24  24  24  24  24  24  24  24  24   0  10   2   0   0   0   0  96   0   0   0   0

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updated Mon Jun 29 11:20:41 2026