8ssr_A : 3D-footprint complex

structure name	ZNFS 3-11 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 35MER DNA 35- 20 (Transcriptional repressor CTCF)
reference	Horton et al. 'Nucleic 51 8447 2023
source	Homo sapiens
experiment	X-ray (resolution=3.14, R-factor=0.251)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
reference complex	8ssq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8ssr_A interface=18,21,25,44,47,50,74,75,78,100,103,130,132,133,136,188,190,191,194,216,218,219,248, trphkcpdcdmafvtsgElvRhrrYkhthekpfkcsmcdyasvEvsKlkRhirshtgerpfqcslcsyasrdtYKlkRhmrthsgekpyecyicharftQsgTmkmhilqkhtenvakfhcphcdtviaRkSDlgVhlrkqhsyieqgkkcrycdavfheryaliqhqkshknekrfkcdqcdyacrQeRHmiMhkrthtgekpyacshcdktfrQkQLldmhfkryhdpnfvpaafvcskcgktftRrntmarhadnca
interface signature	ERYEKRYKRQTRSDVQRHMQQLR

Estimated binding specificities ?

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# IC=14.864 IC/col=0.425 n_of_columns=35

specificity:

A |  24  24  24  13   0   0   3   0  96  16   3   0   2  12  20   4  19  24  24  24  24  24  24  24  22   0  12  18  70  17  16  13   9  60  24
C |  24  24  24  14  96   0  87  96   0  52  85   0   1  60  22   4  20  24  24  24  24  24  24  24  25   0  12  18  10  49  16  13  69  12  24
G |  24  24  24  56   0  96   3   0   0  14   3   0  92  12  20  84  38  24  24  24  24  24  24  24  22  96  60  18   8  15  16  57   9  12  24
T |  24  24  24  13   0   0   3   0   0  14   5  96   1  12  34   4  19  24  24  24  24  24  24  24  27   0  12  42   8  15  48  13   9  12  24

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updated Tue Dec 19 04:52:40 2023