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structure nameZNFS 3-11 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 35MER DNA 35- 20
(Transcriptional repressor CTCF)
referenceHorton et al. 'Nucleic 51 8447 2023
sourceHomo sapiens
experimentX-ray (resolution=3.14, R-factor=0.251)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
multimeric complexes7w1m_ABDEH
reference complex7w1m_H
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureERYEKRYKRQTRSDVQRHMQQLR

Estimated binding specificities ?

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# IC=23.732 IC/col=0.791 n_of_columns=30 specificity:   
A |   2   0   0  69   2   0  62   0  24  24  24  24  24  24  24  24  24  24   0  82   2   0  96   0   0   0   0   0   0   0
C |   4   0  94   8  10   0   8  96  72  24  24  24  24  24  24  24  24  24  96   2   4  96   0   0   0   0   0   0  96   0
G |   5  96   0  11   2   0  10   0   0  24  24  24  24  24  24  24  24  24   0   2  88   0   0  96  96   0  96  96   0  96
T |  85   0   2   8  82  96  16   0   0  24  24  24  24  24  24  24  24  24   0  10   2   0   0   0   0  96   0   0   0   0
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updated Sat Jan 10 01:55:38 2026