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structure nameZNFS 3-11 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 35MER DNA 35- 20
(Transcriptional repressor CTCF)
referenceHorton et al. 'Nucleic 51 8447 2023
sourceHomo sapiens
experimentX-ray (resolution=3.14, R-factor=0.251)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex8ssq_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureERYEKRYKRQTRSDVQRHMQQLR

Estimated binding specificities ?

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# IC=24.028 IC/col=0.801 n_of_columns=30 specificity:   
A |   0   0   0   0  96   0   0   0   0   3   8   0  10  24  24  24  24  24  24  24  24   0   0   8  96  63   6   2   0  87
C |  96   0  96  96   0  96  96   0   0  89   2   0   8  24  24  24  24  24  24  24  24   0   0  15   0  23  10   0  96   0
G |   0  96   0   0   0   0   0   0  96   2   2  96  61  24  24  24  24  24  24  24  24  74  96  10   0   8   6  94   0   5
T |   0   0   0   0   0   0   0  96   0   2  84   0  17  24  24  24  24  24  24  24  24  22   0  63   0   2  74   0   0   4
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updated Fri Sep 13 13:33:36 2024