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structure nameCRYSTAL STRUCTURE OF VDR DNA-BINDING DOMAIN BOUND TO RAT OSTEOCALCIN (OC) RESPONSE ELEMENT
(Vitamin D3 Receptor)
referenceShaffer et al. 'EMBO 21 2242 2002
sourceHomo sapiens
experimentX-ray (resolution=2.70, R-factor=?)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes1kb2_AB 1kb4_AB 1kb6_AB 1ynw_AB
redundant complexes1kb4 1ynw 1kb2
reference complex1kb2_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureEKRRK

Estimated binding specificities ?

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# IC=3.184 IC/col=0.637 n_of_columns=5 specificity:   
A |   0   0  13  24  57
C |   0   0  13  24  13
G |  96  96  13  24  13
T |   0   0  57  24  13
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: VDR
GGGTCAGCAAGTTCAPubMed1kb2_AB(1.87e-05), 1kb4_AB(3.77e-03), 1kb6_AB(3.91e-04), ... (total=5)
TGAACTCAAAGGAGGTCAPubMed1kb2_A(1.04e-03)
AGGTCAPubMed1ynw_AB(2.78e-04), 1kb2_A(1.15e-02)
GGGTGAGCAGGGACAPubMed1kb6_AB(4.00e-04)

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updated Thu Sep 12 14:47:45 2024