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structure nameMETHIONINE REPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO A CONSENSUS OPERATOR SEQUENCE
(PROTEIN METHIONINE REPRESSOR)
referencePhillips et al. 'Structure 8 905 2000
sourceEscherichia coli
experimentX-ray (resolution=2.40, R-factor=0.212)
structural superfamilyRibbon-helix-helix;
sequence familyMet Aporepressor, MetJ;
multimeric complexes1cma_AB 1mj2_ABCD 1mjm_AB 1mjo_ABCD 1mjp_AB 1mjq_ABCD 1mjq_GHIJ
reference complex1mjo_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKTS

Estimated binding specificities ?

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# IC=2.635 IC/col=0.439 n_of_columns=6 specificity:   
A |  67  11  24  24   0   9
C |   9  67  24  24  96  11
G |  11   9  24  24   0   9
T |   9   9  24  24   0  67
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updated Thu Sep 12 14:57:11 2024