1qpi_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF TETRACYCLINE REPRESSOR/OPERATOR COMPLEX (PROTEIN TETRACYCLINE REPRESSOR)
reference	Schnappinger et al. Nat.Struct.Biol. 7 215 2000
source	Escherichia coli
experiment	X-ray (resolution=2.50, R-factor=0.244)
structural superfamily	Tetracyclin repressor-like, C-terminal domain;Homeodomain-like;
sequence family	Tetracyclin repressor, Cterminal allalpha; Bacterial regulatory proteins, tetR family;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1qpi_A interface=25,36,37,40, lnresvidaalellnetgidglttRklaqklgieqPTlyWhvknkralldalaveilarhhdyslpaageswqsflrnnamsfrrallryrdgakvhlgtrpdekqydtvetqlrfmtengfslrdglyaisavshftlgavleqqehtaalenlppllrealqimdsddgeqaflhgleslirgfevqltallq
interface signature	RPTW

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4

specificity:

A |   0  16   0  54
C |  96  54   0  13
G |   0  13   0  13
T |   0  13  96  16

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --RC----PTTC--WC   L                     +-------1qpi_A    
                            +--------------1 
  MTRG--TTMGSCYTYT   L   +--2              +-------3zql_B    
                         !  ! 
  ----SCKGSG--IGYC   L --3  +----------------------2yvh_A    
                         ! 
  TA----ECAC--YCRA       +-------------------------5haw_A

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updated Sun Aug 3 05:52:39 2025