| structure name | HTRF2 DNA-BINDING DOMAIN IN COMPLEX WITH TELOMERIC DNA. (TELOMERIC REPEAT BINDING FACTOR 2) |
| reference | Chapman et al. 'Embo 6 39 2005 |
| source | HOMO SAPIENS |
| experiment | X-ray (resolution=1.80, R-factor=0.220) |
| structural superfamily | Homeodomain-like; |
| sequence family | Myblike DNAbinding domain; |
| multimeric complexes | 1w0u_AB 3sjm_AB |
| reference complex | 1vfc_A |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | KVKDRT |
Estimated binding specificities ?
| readout + contact |  |
A | 88 7 0 0 0 8 96 24 24 24 24 7 75 C | 0 7 96 96 96 7 0 24 24 24 24 9 14 G | 8 7 0 0 0 0 0 24 24 24 24 7 7 T | 0 75 0 0 0 81 0 24 24 24 24 73 0scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: HTRF2 | ||
| TTAGGG | PubMed | 1w0u_A(2.04e-04), 1w0u_AB(2.04e-04) |
Dendrogram of similar interfaces ?
matrix formatRT----------------KTIAQCNA---- L +1ig7_A +-1 RT------------------NT--NAITRG L +----------5 +5zjt_B ! ! RA----------------KGSAQA------ L +---7 +6j5b_C ! ! RT----------STVC--KGDCRG------ L ! ! +1w0t_A ! +-----------2 RA------------------ITQTNAMG-- L +-8 +5zjt_E ! ! --------------------IA--NA---- ! ! +4qtr_D ! ! +-4 RT------------------NT--NAIARG L +---9 +--------------6 +1b72_B ! ! ! RT------------------ITQCNAACRG L ! ! +6a8r_A ! ! ------------YTVC--KGDCKC------ L +--11 +----------------2qhb_A ! ! RT------------------IAKGNA---- L ! ! +2hdd_A ! ! +-----------------3 RT------------------NT--NA--RG L +-12 +-10 +1b8i_B ! ! ! --DT--------RGRCTT----KT------ L ! ! +-----------------2o9l_A +-13 ! RAYA----------------IAQCNAYCKG L ! ! +------------------------5flv_I +-14 ! --------------KG--RTEC-------- L ! ! +---------------------------1h89_C -15 ! ------MTRG-------------------- L ! +-----------------------------3zql_B ! ----YC----KTHGSTQTYTPT-------- L +-----------------------------5x11_A |
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updated Thu Sep 12 15:38:23 2024