interface graph thumbnail
legend  pdf

structure nameSOLUTION STRUCTURE OF THE DNA COMPLEX OF HUMAN TRF2
(TELOMERIC REPEAT BINDING FACTOR 2)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyHomeodomain-like;
sequence familyMyblike DNAbinding domain;
multimeric complexes1w0u_AB 3sjm_AB
redundant complexes1w0u_A 3sjm_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKAVKDR

Estimated binding specificities ?

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# IC=4.072 IC/col=0.582 n_of_columns=7 specificity:   
A |  68  12   0   3  24   3  55
C |  18  11   0   3  24   6  20
G |   3  55  96  84  24   3  14
T |   7  18   0   6  24  84   7
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RA----------------KGSAQA--   L       +-----------------------------6j5b_C    
                                     +-1 
  ----------SGVTSCSGNTRTRT--   L   +-2 +-----------------------------6pax_A    
                                   ! ! 
  --LAHAKARA----------------     --3 +-----------------------------6dta_A    
                                   ! 
  RT------------------IAKGNA   L   +-----------------------------2hdd_A    
                                 

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updated Tue Dec 17 22:28:57 2024