1vfc_A : 3D-footprint complex

structure name	SOLUTION STRUCTURE OF THE DNA COMPLEX OF HUMAN TRF2 (TELOMERIC REPEAT BINDING FACTOR 2)
source	HOMO SAPIENS
experiment	NMR
structural superfamily	Homeodomain-like;
sequence family	Myblike DNAbinding domain;
multimeric complexes	1w0u_AB 3sjm_AB
redundant complexes	1w0u_A 3sjm_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1vfc_A interface=10,47,48,51,52,55, edsttnitkKqkwtveesewvkagvqkygegnwaaisknypfvnrtAVmiKDrwRtmkrlgmn
interface signature	KAVKDR

Estimated binding specificities ?

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# IC=4.274 IC/col=0.611 n_of_columns=7

specificity:

A |  59  13   0   1  24   1  45
C |   2  13   0   0  24   4  20
G |  22  52  96  91  24   0  18
T |  13  18   0   4  24  91  13

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RA----------------KGSAQA--   L       +-----------------------------6j5b_C    
                                     +-1 
  ----------SGVTSCSGNTRTRT--   L   +-2 +-----------------------------6pax_A    
                                   ! ! 
  --LAHAKARA----------------     --3 +-----------------------------6dta_A    
                                   ! 
  RT------------------IAKGNA   L   +-----------------------------2hdd_A

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updated Sat Jan 10 05:01:47 2026