structure nameCRYSTAL STRUCTURE AT 1.7 ANGSTROMS OF THE BOVINE PAPILLOMAVIRUS-1 E2 DNA-BINDING DOMAIN BOUND TO ITS DNA TARGET
(PROTEIN E2)
referenceGrossman et al. Nature 359 505 1992
sourceBovine papillomavirus type 1
experimentX-ray (resolution=1.70, R-factor=0.201)
structural superfamilyViral DNA-binding domain;
sequence familyE2 early protein, C terminal;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNKCF

Estimated binding specificities ?

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# IC=3.360 IC/col=0.840 n_of_columns=4 specificity:   
A |   7   0   0  16
C |  74   0   0  16
G |   7  96  96  19
T |   8   0   0  45
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: E2
ACCGNPubMed2bop_A(1.38e-04)
ATCGGTGPubMed2bop_A(1.03e-03)
AACCGNPubMed2bop_A(3.66e-04)

Dendrogram of similar interfaces ?

matrix format
  
  ----KGCGFT----   L                 +--2bop_A    
                               +-----1 
  --NCKGCAYGRA--   L   +-------2     +--2ayg_A    
                       !       ! 
  KGTAYCNGRT----   L --3       +--------5t7x_B    
                       ! 
  ------------RC   L   +----------------2itl_B

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updated Sun Aug 3 06:08:55 2025