2qkb_A : 3D-footprint complex

structure name	HUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 20-MER RNA/DNA HYBRID (Ribonuclease H1)
reference	Gaidamakov et al. Mol.Cell 28 264 2007
source	Homo sapiens
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Ribonuclease H-like;
sequence family	RNase H;
multimeric complexes	2qkb_AB 2qkk_JW 2qkk_NS
redundant complexes	2qk9_A 2qkk_M
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2qkb_A interface=19,21,50,51,81,89,101, gshmgdfvvvytdgccssNgRrrpragigvywgpghplnvgirlpgrqtNQraeihaackaieqaktqninklvlytnsmFtingitnWvqgwkkngwktSagkevinkedfvalerltqgmdiqwmhvpghsgfigneeadrlaregakqs
interface signature	NRNQFWS

Estimated binding specificities ?

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# IC=6.010 IC/col=0.859 n_of_columns=7

specificity:

A |  12   6   0   0  19  14   0
C |   6   6   0   0  51  12  96
G |  78   8  96   0   6  64   0
T |   0  76   0  96  20   6   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  NT--RGNGQGFTWCSC   L            +-------------2qkb_A    
                         +--------2 
  --NC------------       !        +-------------4htu_B    
                       --3 
  ----PT----------       !                     +5chi_C    
                         +---------------------1 
  --------RT------                             +4yoy_E

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updated Tue Dec 19 06:54:01 2023