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legend  pdf

structure nameCRYSTAL STRUCTURE OF A REX-FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN FROM STREPTOCOCCUS AGALACTIAE BOUND TO A PALINDROMIC OPERATOR
(Redox-sensing transcriptional repressor rex)
referencevon Wachenfeldt et al. 'Plos 17 e1009791 2021
sourceStreptococcus agalactiae serogroup III
experimentX-ray (resolution=2.40, R-factor=0.198)
structural superfamilyNADP-binding Rossmann-fold domains;"Winged helix" DNA-binding domain;
sequence familyCoA binding domain; Putative DNAbinding protein Nterminu;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureATRRSYR

Estimated binding specificities ?

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# IC=8.762 IC/col=0.974 n_of_columns=9 specificity:   
A |  66   0   0   0   0   0  84  48  72
C |  12   0   0   0   0   0  12  18  12
G |  12   0   0  96   0  96   0  18   6
T |   6  96  96   0  96   0   0  12   6
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: REX
TTGTGAANNNNTTCACAAPubMed3ket_A(1.00e-05)
TTCACAAPubMed3ket_A(9.46e-11)

Dendrogram of similar interfaces ?

matrix format
  
  ------ATTTRGRGSTYTRA--   L                               +3ket_A    
                                            +--------------1 
  ------SAQTRGQTNG--QT--   L      +---------2              +3wgi_D    
                                  !         ! 
  ------SC--RGKGST--RAVA   L   +--3         +--------------7wb3_B    
                               !  ! 
  RGHCRGRGQA------------   L --4  +------------------------2glo_A    
                               ! 
  RT--STVC--KGDCRG------   L   +---------------------------1w0t_A    
                             

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updated Fri Sep 13 17:20:06 2024