3ket_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A REX-FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN FROM STREPTOCOCCUS AGALACTIAE BOUND TO A PALINDROMIC OPERATOR (Redox-sensing transcriptional repressor rex)
reference	von Wachenfeldt et al. 'Plos 17 e1009791 2021
source	Streptococcus agalactiae serogroup III
experiment	X-ray (resolution=2.40, R-factor=0.198)
structural superfamily	NADP-binding Rossmann-fold domains;"Winged helix" DNA-binding domain;
sequence family	CoA binding domain; Putative DNAbinding protein Nterminu;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3ket_A interface=42,43,45,46,49,50,57, sipkatakrlslyyrifkrfntdgiekasskqiadalgidsATvRRdfSYfgelgrRgfgydvkklmnffaeilndhsttnvmlvgcgnigrallhyrfhdrnkmqismafdldsndlvgkttedgipvygistindhlidsdietailtvpsteaqevadilvkagikgilsfspvhltlpkdiivqyvdltselqtllyfmnq
interface signature	ATRRSYR

Estimated binding specificities ?

readout + contact

# IC=8.776 IC/col=0.975 n_of_columns=9

specificity:

A |  66   0   0   0   0   0  90  48  66
C |  12   0   0   0   0   0   6  18  12
G |  12   0   0  96   0  96   0  18   6
T |   6  96  96   0  96   0   0  12  12

scan!

Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: REX
TTGTGAANNNNTTCACAA	PubMed	3ket_A(1.00e-05)
TTCACAA	PubMed	3ket_A(9.46e-11)

Dendrogram of similar interfaces ?

matrix format

  
  ------ATTTRGRGSTYTRA--   L                               +3ket_A    
                                            +--------------1 
  ------SAQTRGQTNG--QT--   L      +---------2              +3wgi_D    
                                  !         ! 
  ------SC--RGKGST--RAVA   L   +--3         +--------------7wb3_B    
                               !  ! 
  RGHCRGRGQA------------   L --4  +------------------------2glo_A    
                               ! 
  RT--STVC--KGDCRG------   L   +---------------------------1w0t_A

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updated Sat Jan 10 06:11:23 2026