interface graph thumbnail
legend  pdf

structure nameHTRF1 DNA-BINDING DOMAIN IN COMPLEX WITH TELOMERIC DNA.
(TELOMERIC REPEAT BINDING FACTOR 1)
referenceChapman et al. 'Embo 6 39 2005
sourceHOMO SAPIENS
experimentX-ray (resolution=2.00, R-factor=0.252)
structural superfamilyHomeodomain-like;
sequence familyMyblike DNAbinding domain;
multimeric complexes1w0t_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSVKDR

Estimated binding specificities ?

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# IC=4.039 IC/col=0.808 n_of_columns=5 specificity:   
A |  64  64  10   0   0
C |  10  12  74  96  96
G |  10  10  10   0   0
T |  12  10   2   0   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: HTRF1
TTAGGGPubMed1w0t_AB(1.77e-04)
TTTAGGGPubMed1w0t_AB(1.69e-03)
GGTTTAGPubMed1w0t_A(1.05e-03)

Dendrogram of similar interfaces ?

matrix format
  
  RT----------QTVAQTNA--   L                                   +8osb_E    
                                                            +--1 
  RT------------VTKGNA--   L              +-----------------2  +2lkx_A    
                                          !                 ! 
  RT------------IAQCNAMG   L     +--------3                 +--1b72_A    
                                 !        ! 
  RC------------IAQCNAYC   L   +-4        +--------------------3rkq_B    
                               ! ! 
  --NG--RGKG--SGSAQAVC--   L --5 +-----------------------------5no6_N    
                               ! 
  ----NA--RTQT--EC------   L   +-----------------------------2kdz_A

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updated Mon Jun 29 14:46:03 2026