interface graph thumbnail
legend  pdf

structure nameMITF:E-BOX COMPLEX
(MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR)
referencePogenberg et al. 'Genes 26 2647 2012
sourceMUS MUSCULUS
experimentX-ray (resolution=2.95, R-factor=0.255)
structural superfamilyHLH, helix-loop-helix DNA-binding domain;
sequence familyHelixloophelix DNAbinding domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHNERR

Estimated binding specificities ?

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# IC=4.007 IC/col=0.801 n_of_columns=5 specificity:   
A |  67   0   0  69   9
C |   9   0  96   9  67
G |   9  96   0   9   9
T |  11   0   0   9  11
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updated Mon Dec 16 22:46:31 2024