interface graph thumbnail
legend  pdf

structure nameMITF:E-BOX COMPLEX
(MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR)
referencePogenberg et al. 'Genes 26 2647 2012
sourceMUS MUSCULUS
experimentX-ray (resolution=2.95, R-factor=0.255)
structural superfamilyHLH, helix-loop-helix DNA-binding domain;
sequence familyHelixloophelix DNAbinding domain;
multimeric complexes4ati_AB 4atk_AB
reference complex6g1l_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHNERR

Estimated binding specificities ?

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# IC=3.968 IC/col=0.794 n_of_columns=5 specificity:   
A |  67   0   0  67   9
C |  11   0  96   9  67
G |   9  96   0  11   9
T |   9   0   0   9  11
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updated Sat Aug 2 05:46:12 2025