interface graph thumbnail
legend  pdf

structure nameDNA BINDING BY GATA TRANSCRIPTION FACTOR-COMPLEX 3
(Trans-acting T-cell-specific transcription factor GATA-3)
referenceBates et al. 'Cell 2 1197 2012
sourceHomo sapiens
experimentX-ray (resolution=1.60, R-factor=?)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyGATA zinc finger;
redundant complexes4hc7_A 4hca_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signaturePLRNL

Estimated binding specificities ?

contactlogo
# IC=3.142 IC/col=0.786 n_of_columns=4 specificity:   
A |  57   0  16  96
C |  13   0  54   0
G |  13   0  13   0
T |  13  96  13   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: GATA
AGATAAPubMed4hc7_A(9.43e-07), 4hca_A(4.32e-05)
TTATCTPubMed4hc7_A(9.43e-07), 4hca_A(4.32e-05)
CGATAPubMed4hc7_A(3.54e-04), 4hca_A(2.91e-03)
GATAAPubMed4hc7_A(1.29e-07), 4hca_A(4.08e-06)
AGATAPubMed4hc7_A(3.54e-04), 4hca_A(2.91e-03)
AGATAGPubMed4hc7_A(1.12e-03), 4hca_A(1.02e-02)
TATAAAPubMed4hc7_A(1.18e-03), 4hca_A(1.09e-02)
TGATAAPubMed4hc9_A(3.59e-04), 4hc7_A(4.35e-11), 4hca_A(1.49e-08)
GACAAGATAAPubMed4hc7_A(7.15e-05), 4hca_A(7.88e-03)
GATAAGPubMed4hc7_A(9.43e-07), 4hca_A(4.32e-05)

Dendrogram of similar interfaces ?

matrix format
  
  PTLCRGNALA----------------   L   +-------------4hc9_A    
                                   ! 
  ----------TTLGRGNALA--LTRT   L --3           +-3dfx_B    
                                   !         +-1 
  ----------TTLARGNTLT--LT--   L   +---------2 +-2gat_A    
                                             ! 
  ------------LCRG--LAFTLTRG                 +---4gat_A

home
updated Tue Dec 19 08:55:26 2023