3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

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updated Mon Jan 5 09:54:30 2026

structure name	CRYSTAL STRUCTURE OF HETEROCHROMATIN PROTEIN SIR3 IN COMPLEX WITH A SILENCED YEAST NUCLEOSOME
reference	Mohammed et al. Proc.Natl.Acad.Sci.USA 110 8495 2013
source	SACCHAROMYCES CEREVISIAE
experiment	X-ray (resolution=3.09, R-factor=?)
structural superfamily	Histone-fold;Nucleic acid-binding proteins;P-loop containing nucleoside triphosphate hydrolases;
reference complex	7e9c_A 7e9c_D 7e9c_F 7e9c_G 8xgc_4
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4jjn_A interface=2,3,28,46, pHRykpgtvalreirrfqkstellirkLpfqrlvreiaqdfktdlRfqssaigalqesveaylvslfedtnlaaihakrvtiqkkdiklarrlrgers > 4jjn_B interface=32, gakrhrkilrdniqgitkpairrlarrggvkRisgliyeevravlksflesvirdsvtytehakrktvtsldvvyalkrqgrtlygfgg > 4jjn_C interface= asqsrsakagltfpvgrvhrllrrgnyaqriGsgapvyltavleylaaeilelagnaardnkktriiprhlqlairnddelnkllgnvtiaqggvlpnihqnllp > 4jjn_D interface=3, kvRketyssyiykvlkqthpdtgisqksmsilnsfvndiferiateasklaaynkkstisareiqtavrlilpgelakhavsegtravtkyssst > 4jjn_E interface=3,45, hrYkpgtvalreirrfqkstellirklpfqrlvreiaqdfktdlRfqssaigalqesveaylvslfedtnlaaihakrvtiqkkdiklarrlrger > 4jjn_F interface=24, kggakrhrkilrdniqgitkpaiRrlarrggvkrisgliyeevravlksflesvirdsvtytehakrktvtsldvvyalkrqgrtlygfgg > 4jjn_G interface=28, qsrsakagltfpvgrvhrllrrgnyaqRigsgapvyltavleylaaeilelagnaardnkktriiprhlqlairnddelnkllgnvtiaqggvlpnihqnllpkks > 4jjn_H interface= ketyssyiykvlkqthpdtgisqksmsIlnsfvndiferiateasklaaynkkstisareiqtavrlilpgelakhavsegtravtkyssst