interface graph thumbnail
legend  pdf

structure nameTBX5 DB, NKX2.5 HD, ANF DNA COMPLEX
(HOMEOBOX PROTEIN NKX-2.5)
referenceBiochemistry 55 1702 2016
sourceHOMO SAPIENS
experimentX-ray (resolution=2.82, R-factor=0.195)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes3rkq_AB 4s0h_AB 4s0h_EF
reference complex3rkq_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRIQNY

Estimated binding specificities ?

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# IC=2.199 IC/col=0.314 n_of_columns=7 specificity:   
A |  20   8  56  70   8  21  10
C |  19   8  14   8   8  21  10
G |  19  70  13  10  72  23  63
T |  38  10  13   8   8  31  13
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updated Thu Sep 12 20:05:18 2024