4umm_AE : 3D-footprint complex

structure name	THE CRYO-EM STRUCTURE OF THE PALINDROMIC DNA-BOUND USP-ECR NUCLEAR RECEPTOR REVEALS AN ASYMMETRIC ORGANIZATION WITH ALLOSTERIC DOMAIN POSITIONING
reference	Billas et al. Nat.Commun. 5 4139 2014
source	HELIOTHIS VIRESCENS
experiment	X-ray (resolution=11.60, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;Nuclear receptor ligand-binding domain;
reference complex	2han_A 4umm_E 4umm_F 4umm_G
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4umm_A interface=22,25,29,30,78, khlcsicgdrasgkhygvyscEgcKgffKRtvrkdltyacreernciidkrqrnrcqycryqkclacgmkreavqeeR > 4umm_E interface=25,28,32,33,57, rqqeelclvcgdrasgyhynaltcEgcKgffRRsvtknavyickfghacemdmymrRkcqecrlkkclavgmrpecvvpenqcamkr
interface signature	EKKRR/EKRRR

Estimated binding specificities ?

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# IC=7.377 IC/col=0.671 n_of_columns=11

specificity:

A |   0   6  24  24  48  24   1   0  50  96   0
C |   0   2  24  24  13  24   6   0  13   0  96
G |  96  13  24  24  13  24   0  96  13   0   0
T |   0  75  24  24  22  24  89   0  20   0   0

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updated Wed Jul 30 02:54:09 2025