3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.

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updated Mon Jan 5 11:29:40 2026

structure name	CRYSTAL STRUCTURE OF CENP-C IN COMPLEX WITH THE NUCLEOSOME CORE PARTICLE
reference	Science 340 1110 2013 Escherichia coli
source	DROSOPHILA MELANOGASTER
experiment	X-ray (resolution=3.50, R-factor=?)
structural superfamily	Histone-fold;lambda repressor-like DNA-binding domains;p53-like transcription factors;
reference complex	4x23_V 5o9g_F 6pwe_G 6pwe_H 6r8y_H 6x0n_f 7ccr_A 7nkx_f 7u0g_M 7vdt_B 7xzx_N 8wg5_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4x23_A interface=2, rYrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqssavmalqeaseaylvglfedtnlcaihakrvtimpkdiqlarrirgie > 4x23_B interface= dNiqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 4x23_C interface=27, srsnraglqfpvgrihrllrkgnyaeRvgagapvylaavmeylaaevlelagnaardnkktriiprhlqlairndeelnkllsgvtiaqggvlpniqavllp > 4x23_D interface= esyaiyiykvlkqvhpdtgisskamsImnsfvndiferiaaeasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytss > 4x23_E interface=44, ryrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlRfqssavmalqeaseaylvglfedtnlcaihakrvtimpkdiqlarrirgieggl > 4x23_F interface=22, dniqgitkpairrlarrggvkRisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 4x23_G interface=27, srsnraglqfpvgrihrllrkgnyaeRvgagapvylaavmeylaaevlelagnaardnkktriiprhlqlairndeelnkllsgvtiaqggvlpniqavllp