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3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.

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updated Wed Jun 24 23:10:10 2026

structure name	CRYSTAL STRUCTURE OF CENP-C IN COMPLEX WITH THE NUCLEOSOME CORE PARTICLE
reference	Science 340 1110 2013 Escherichia coli
source	DROSOPHILA MELANOGASTER
experiment	X-ray (resolution=3.50, R-factor=?)
structural superfamily	Histone-fold;lambda repressor-like DNA-binding domains;p53-like transcription factors;
reference complex	4x23_V 5o9g_E 5o9g_F 6a5l_e 6ir9_e 6nqa_A 6pwe_G 6pwe_H 6pww_K 6r8y_H 6x0n_f 6yov_C 7eg6_A 7egp_S 7nkx_a 7nkx_f 7u0g_M 7unc_a 7und_e 7vdt_B 7xsx_a 7xzx_N 7zs9_e 8aag_A 8atf_Q 8bvw_e 8ceo_r 8he5_a 8jh2_e 8jhf_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4x23_K interface= ryrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqssavmalqeaseaylvglfedtnlcaihakrvtimpkdiqlarrirgie > 4x23_L interface= dniqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 4x23_M interface=27,60, srsnraglqfpvgrihrllrkgnyaeRvgagapvylaavmeylaaevlelagnaardnkKtriiprhlqlairndeelnkllsgvtiaqggvlpniqavllp > 4x23_N interface= esyaiyiykvlkqvhpdtgisskamsImnsfvndiferiaaeasrlahynkrstitsreIqtavrlllpgelakhavsegtkavtkytss > 4x23_O interface=4,44, ryrPgtvalreirryqkstellirklpfqrlvreiaqdfktdlRfqssavmalqeaseaylvglfedtnlcaihakrvtimpkdiqlarrirgieggl > 4x23_P interface= dniQgitkpairrlarrggvkrisgliyeetrgvlkvflenviRdavtytehakrktvtamdvvyalkrqgrtlygfgg > 4x23_Q interface=20,27, srsnraglqfpvgrihrllRkgnyaeRvgagapvylaavmeylaaevlelagnaardnkktriiprhlqlairndeelnkllsgvtiaqggvlpniqavllp