3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

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updated Tue Sep 10 03:00:29 2024

structure name	NUCLEOSOME CORE PARTICLE WITH ADDUCTS FROM THE ANTICANCER COMPOUND, [(ETA6-5,8,9,10-TETRAHYDROANTHRACENE)RU(ETHYLENEDIAMINE)CL][PF6]
reference	Adhireksan et al. Angew.Chem.Int.Ed.Engl. 55 7441 2016
source	XENOPUS LAEVIS
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	Histone-fold;lambda repressor-like DNA-binding domains;p53-like transcription factors;Nucleic acid-binding proteins;P-loop containing nucleoside triphosphate hydrolases;
reference complex	1kx5_G 5o9g_E 5o9g_F 5x0y_D 5z3u_A 6ftx_B 6iro_A 6nqa_A 6pww_K 6r25_E 6r8y_H 6x0n_f 6yov_C 7at8_D 7eg6_A 7egp_S 7nkx_a 7nkx_f 7otq_E 7u0g_M 7unc_a 7und_e 7vdt_B 7xcr_F 7xzx_N 7xzz_N 7zs9_e 8a3y_a 8aag_A 8atf_Q 8bvw_e 8byq_e 8ceo_r 8cww_A 8g57_E 8he5_a 8jh2_e 8jhf_A 8siy_G 8xgc_4
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5cp6_A interface=2,3,28,46, pHRyrpgtvalreirryqkstellirkLpfqrlvreiaqdfktdlRfqssavmalqeaseaylvalfedtnlcaihakrvtimpkdiqlarrirge > 5cp6_B interface=25, vlrdniqgitkpairrlarrggvkRisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 5cp6_C interface= aktrssraglqfpvgrvhrllrkgNyaervgagapvylaavleyltaeilelagnaardnkktriiprhlqlavrndeelnkllgrvtiaqggvlpniqsvllpkk > 5cp6_D interface= ktrkesyaiyvykvlkqvhpdtgiSskamsimnsfvndvferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsak > 5cp6_E interface=2,3,28, pHRyrpgtvalreirryqkstellirkLpfqrlvreiaqdfktdlrfqssavmalqeaseaylvalfedtnlcaihakrvtimpkdiqlarrirge > 5cp6_F interface=30, krhrkvlrdniqgitkpairrlarrggvkRisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 5cp6_G interface= aktrssraglqfpvgrvhrllrkgnyaerVgagapvylaavleyltaeilelagnaardnkktriiprhlqlavrndeelnkllgrvtiaqggvlpniqsvllpkk > 5cp6_H interface=3, ktRkesyaiyvykvlkqvhpdtgisskamsimnsfvndvferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsak