5d8c_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HINMLR, A MERR FAMILY REGULATOR LACKING THE SENSOR DOMAIN, BOUND TO PROMOTER DNA (MerR family regulator protein)
reference	Counago et al. 'Nucleic 44 6981 2016
source	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) / Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) / Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
experiment	X-ray (resolution=2.25, R-factor=0.209)
structural superfamily	Putative DNA-binding domain;
sequence family	MerR family regulatory protein;
multimeric complexes	5d8c_AB 5e01_AB
redundant complexes	5e01_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5d8c_A interface=17,20,21,24, mtyttakaaekigisaYtlRFydKegllpnvgrdeygnrrftdkdlqwlsllqclkntgmslkdikrfaectiigddtieerlslfenqtknvkcqiaelkryldlleyklafyqkakalgsvkav
interface signature	YRFK

Estimated binding specificities ?

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# IC=4.007 IC/col=0.668 n_of_columns=6

specificity:

A |   9  24  67   0  67   0
C |   9  24  11   0   9   0
G |   9  24   9  96   9  96
T |  69  24   9   0  11   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  YTRTFCKG--   L             +--------5d8c_A    
                     +-------3 
  EARTYARTYG   L     !       !  +-----6jgx_B    
                     !       +--2 
  RGHTHC--YG   L   +-4          +-----1r8d_B    
                   ! ! 
  RGRTYT--KT   L   ! !               +7tea_B    
                 --5 +---------------1 
  RCRT------       !                 +7tec_A    
                   ! 
  RART------       +------------------4r24_B

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updated Fri Sep 13 19:26:34 2024