5u30_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF AACC2C1-SGRNA-EXTENDED TARGET DNA TERNARY COMPLEX (CRISPR-associated endonuclease C2c1)
reference	Rajashankar et al. Cell 167 1814 2016
source	Alicyclobacillus acidoterrestris
experiment	X-ray (resolution=2.92, R-factor=0.207)
redundant complexes	5u33_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5u30_A interface=119,120,123,143,145,207,217,399, smavksikvklrlddmpeiraglwklhkevnagvryytewlsllrqenlyrrspngdgeqecdktaeeckaellerlrarqvenghrgpagsddellqlarqlyellvpqaigakgdaQQiaRkflspladkdavgglgiakAgNkprwvrmreageweeekekaetrksadrtadvlraladfglkplmrvytdsemssvewkplRkgqavrtwdRdmfqqaiermmsweswnqrvgqeyaklveqknrfeqknfvgqehlvhlvnqlqqdmkeaspgleskeqtahyvtgralrgsdkvfekwgklapdapfdlydaeiknvqrrntrrfgshdlfaklaepeyqalwredasfltryavynsilrklnhakmfatftlpdatahpiwtrfdklggNlhqytflfnefgerrhairfhkllkvengvarevddvtvpismseqldnllprdpnepialyfrdygaeqhftgefggakiqcrrdqlahmhrrrrdvylnvsvrvqsqseargerrppyaavfrlvgdnhrafvhfdklsdylaehpddgklgsegllsglrvmsvalglrtsasisvfrvarkdelkpnskgrvpfffpikgndnlvavhersqllklpgeteskdlraireerqrtlrqlrtqlaylrllvrcgsedvgrrerswaklieqpvdaanhmtpdwreafenelqklkslhgicsdkewmdavyesvrrvwrhmgkqvrdwrkdvrsgerpkirgyakdvvggnsieqieylerqykflkswsffgkvsgqviraekgsrfaitlrehidhakedrlkkladriimealgyvyaldergkgkwvakyppcqlillaelseyqfnndrppsennqlmqwshrgvfqelinqaqvhdllvgtmyaafssrfdartgapgircrrvparctqehnpepfpwwlnkfvvehtldacplraddliptgegeifvspfsaeegdfhqihaalnaaqnlqqrlwsdfdisqirlrcdwgevdgelvliprltgkrtadsysnkvfytntgvtyyerergreksvvlmrdpsgiinrgnwtrqkefwsmvnqriegylvkqirs
interface signature	QQRANRRN

Estimated binding specificities ?

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# IC=3.610 IC/col=0.902 n_of_columns=4

specificity:

A |  19   0   5   0
C |  19   0   3  96
G |  39   0   3   0
T |  19  96  85   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  TGSGNGQCNGYTSTRADCDCRG--------SCWC--RALATADT--SANARGTGVARTMT   L        +------------------------5wti_Z    
                                                                       +--1 
  IT------------------------------------------QG--------------       +-2  +------------------------6lu0_A    
                                                                     ! ! 
  --------------------VTLT----------KC------------------------   L --3 +---------------------------7lyt_A    
                                                                     ! 
  ----------------------NGATSTRG------------------------------       +-----------------------------5szx_B

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updated Wed Dec 18 02:22:37 2024