5xfp_B : 3D-footprint complex

structure name	BINARY COMPLEX OF PHF1 AND A DOUBLE STRANDED DNA (PHD finger protein 1)
reference	Wang et al. Nature 549 287 2017
source	Homo sapiens
experiment	X-ray (resolution=2.30, R-factor=0.211)
structural superfamily	FYVE/PHD zinc finger;Tudor/PWWP/MBT;
sequence family	PHDfinger;
redundant complexes	5xfq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5xfp_B interface=288,289, rlwegqdvlarwtdgllylgtikkvdsarevclvqfeddsqflvlwkdispaalpgeellccvcrsetvvpgnrlvscekcrhayhqdchvprapapswvcrqcvfaiatkrggalkkgpyaramlgmklslpyglkgldwdaghlsnrqqsycycggpgewnlkmlqcrsclqwfheactqclskpllygdrfyefeccvcrggpekvrrlqlrwvdvahlvlyhlsvcckkkyfdfdreilpftsenwdslllgelsdtpkgerssrllsalnshkdrfisgreiKKrkclfglharmpppve
interface signature	KK

Estimated binding specificities ?

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# IC=2.759 IC/col=0.552 n_of_columns=5

specificity:

A |   9   5   3   8  12
C |  82  81  21  71  41
G |   4   6  68   8  23
T |   1   4   4   9  20

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Dendrogram of similar interfaces ?

matrix format

  
  ----NASTRTHT--ST----   L       +-----------------------------3l2c_A    
                               +-1 
  ----NASTRGHT--ST----   L   +-2 +-----------------------------2uzk_A    
                             ! ! 
  ----NASTRGHT--STLT--   L --3 +-----------------------------2c6y_A    
                             ! 
  ECKTRGAT--RGHT----RA   L   +-----------------------------4mhg_A

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updated Sun Aug 3 10:27:37 2025