interface graph thumbnail
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structure nameCRYSTAL STRUCTURE OF THE FORKHEAD DOMAIN OF HUMAN FOXN1 IN COMPLEX WITH DNA
(Forkhead box protein N1)
referenceStructural Genomics Consortium (SGC)
sourceHomo sapiens
experimentX-ray (resolution=1.61, R-factor=0.196)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHS

Estimated binding specificities ?

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# IC=5.766 IC/col=0.961 n_of_columns=6 specificity:   
A |  16  54   0   0   0   0
C |  13  16  96   0  96  96
G |  13  13   0  96   0   0
T |  54  13   0   0   0   0
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Dendrogram of similar interfaces ?

matrix format
  
  ------------NAST--RGHT--STLT------   L                            +------7cby_C    
                                                                 +--1 
  ------------NAST--RTHT--ST--------   L                  +------2  +------3l2c_A    
                                                          !      ! 
  --------STRTSTHG------------------   L              +---3      +---------3zpl_B    
                                                      !   ! 
  RT--LANTTTETYTRG------------------   L        +-----4   +----------------1f4k_B    
                                                !     ! 
  --TT----KATTQTTG----LTRT----KAFTYT   L     +--5     +--------------------2p7c_B    
                                             !  ! 
  ----------KT--RGAT--RGNT----------   L   +-6  +--------------------------8smh_F    
                                           ! ! 
  ----------SA----------------------     --7 +-----------------------------2xcr_U    
                                           ! 
  --------------------YG------------       +-----------------------------3eyi_B    
                                         

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updated Fri Sep 13 21:35:53 2024