| structure name | CO-CRYSTAL STRUCTURE OF THE HNF-3/FORK HEAD DNA-RECOGNITION MOTIF RESEMBLES HISTONE H5 (HNF-3FORK HEAD DNA-RECOGNITION MOTIF) |
| reference | Burley et al. Nature 364 412 1993 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.50, R-factor=0.211) |
| structural superfamily | "Winged helix" DNA-binding domain; |
| sequence family | Fork head domain; |
| multimeric complexes | 7vox_CH |
| reference complex | 7vox_H |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | NSRHSFRR |
Estimated binding specificities ?
| readout + contact |  |
A | 0 0 56 24 24 0 16 96 48 C | 96 0 8 24 24 0 64 0 16 G | 0 0 16 24 24 0 8 0 16 T | 0 96 16 24 24 96 8 0 16scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: HNF-3 | ||
| TGGACTTAGTTCA | PubMed | 1vtn_C(2.16e-03) |
Dendrogram of similar interfaces ?
matrix format------------------------NAST--RGHT--STFT------------RTRA L +-1vtn_C +---------2 ------------------------------RGHT--ST------------------ L ! +-6akp_C +---6 ------------------------NGSA--RGHG--SC------------------ L ! ! +--6el8_A ! +--------4 ----------------------QTNAST--RGHTNT----STLA------------ L +---9 +--2hdc_A ! ! ------------------------NAST--RGHT--ST------------------ L ! ! +3g73_A ! ! +-1 ------------------------NAST--RGHTNTSTLT---------------- L +----10 +------------5 +7fj2_B ! ! ! ------------------------NAST--RTHT--STLT---------------- L ! ! +--4lg0_A +-12 ! ------------------------NAST--RTHTNTSTLT---------------- L ! ! +-------------------3co6_C ! ! --------YC----KTHGSTQT--YTPT--------------------LG------ L +-13 +-------------------------5x11_A ! ! --------------TT----RT----------------------SGRT--KT---- L ! ! +----------------------2v1u_A +-14 +--11 --RGRTKG------------------------------------------------ L ! ! +----------------------6lui_A ! ! --------------------KT----RGAT--RGYA-------------------- L +-15 ! +-------------4iri_A ! ! +-------------8 ------------NT--TCTA------------------------------------ L ! ! +-------------5zux_A +-16 ! ------------------SGTT--TTYC---------------------------- L ! ! +---------------------------5f7q_C +-17 ! MG------------TGQAAT----SA------RG---------------------- L ! ! +----------------------------2p5l_D ! ! --------SGQG----YCNC------------------------------------ +-18 +----------------------------2ve9_C ! ! ------------------SA------------------------------------ ! ! +-3l4j_A -19 +--------------------------3 ----------------QAAG------------------------------------ L ! +-5zen_A ! --------------------NG----RGRG-------------------------- L ! +-----------1cf7_B +----------------7 --------------------------------YG---------------------- +-----------2heo_D |
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updated Mon Dec 16 19:00:46 2024