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legend  pdf

structure nameCRYSTAL STRUCTURE OF BACILLUS SUBTILIS SIGW DOMAIN 4 IN COMPLEXED WITH -35 ELEMENT DNA
(ECF RNA polymerase sigma factor SigW)
referenceDevkota et al. 'Plos 14 e0221666 2019
sourceBacillus subtilis (strain 168) / Bacillus subtilis (strain 168)
experimentX-ray (resolution=3.10, R-factor=0.250)
structural superfamilySigma3 and sigma4 domains of RNA polymerase sigma factors;
sequence familySigma70, region 4;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureLTKTHR

Estimated binding specificities ?

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# IC=5.710 IC/col=0.952 n_of_columns=6 specificity:   
A |   0   0  13   0   0  68
C |   0   0  16  14  96   0
G |  96   0  13   0   0  13
T |   0  96  54  82   0  15
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Dendrogram of similar interfaces ?

matrix format
  
  ----LG------TAKGTAHTRG--   L                          +6jhe_A    
                                         +--------------1 
  PCFCYG------TGMGSG--RGQC          +----2              +5zx2_F    
                                    !    ! 
  ----LTTTRGECRCRTQC------   L   +--3    +--------------4xln_F    
                                 !  ! 
  ------TTRG--ATSTQC--RG--   L --4  +-------------------2w7n_B    
                                 ! 
  ----------RTTCDTSCSGKG--   L   +----------------------5x5l_H    
                               

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updated Fri Sep 13 22:11:14 2024