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legend  pdf

structure nameCRYSTAL STRUCTURE OF RESPONSE REGULATOR ADER DNA BINDING DOMAIN IN COMPLEX WITH AN INTERCISTRONIC REGION
(ADER)
reference'Nucleic 45 9773 2017 X-RAY DIFFRACTION
sourceACINETOBACTER BAUMANNII
experimentX-ray (resolution=2.75, R-factor=0.279)
structural superfamilyC-terminal effector domain of the bipartite response regulators;
sequence familyTranscriptional regulatory protein, C ter;
multimeric complexes5x5l_AE 5x5l_BH
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRTDSSKR

Estimated binding specificities ?

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# IC=7.704 IC/col=0.856 n_of_columns=9 specificity:   
A |  84  78  24   6   0   6   0   0  18
C |   6   6  24   0   0   6   0   0   6
G |   0   6  24  84   0  84   0  96  60
T |   6   6  24   6  96   0  96   0  12
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --------NTVC--ECSTYT--STYC----------RA--   L                     +------------------5ed4_A    
                                                           +-------4 
  ------------RG----DTVT----STRG------WT--   L             !       !   +--------------6lxn_A    
                                                           !       +---2 
  ------------------------RC----YG--KT----                 !           +--------------2acj_B    
                                                        +--7 
  --------------RCTT----TTHT--LA----------   L          !  ! +------------------------7e1b_B    
                                                        !  ! ! 
  ------------------------------YGRG------              !  ! !                      +-4wcg_A    
                                                        !  +-6        +-------------1 
  RC--------------------------------------            +-8    !   +----3             +-6l9z_S    
                                                      ! !    !   !    ! 
  --ETNT------SCRGHC----RT------------QA--            ! !    +---5    +---------------5d4s_B    
                                                      ! !        ! 
  --EGRG------SARGMCTT--RT----------------   L      +-9 !        +--------------------4wwc_B    
                                                    ! ! ! 
  ------SGAAEC--SAKG----RG--------------RG   L      ! ! +-----------------------------7rva_C    
                                                 +-10 ! 
  ----------TC--KTTC--KGTCHT--ST----------   L   !  ! +-----------------------------7ve5_B    
                                               -11  !  
  --LG------TA--KGTA----HTRG--------------   L   !  +-----------------------------6jhe_A    
                                                 !  
  ----------------NT------NA----ITRG------       +-----------------------------5zjt_B    
                                               

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updated Fri Sep 13 20:54:07 2024