interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF FOXO1-DBD HOMODIMER BOUND TO A PALINDROMIC DNA SEQUENCE
referenceChen et al. 'Nucleic 49 3573 2021
experimentX-ray (resolution=3.07, R-factor=0.229)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
multimeric complexes4lg0_AB 5dui_AB 6lbi_CD 6lbi_GH 6lbi_KL
reference complex3co6_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHS

Estimated binding specificities ?

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# IC=5.766 IC/col=0.961 n_of_columns=6 specificity:   
A |   0  16  13   0   0  96
C |   0  13  16   0   0   0
G |   0  54  13   0   0   0
T |  96  13  54  96  96   0
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updated Fri Sep 13 00:44:47 2024