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structure nameHUMAN TCF4 C-TERMINAL BHLH DOMAIN IN COMPLEX WITH 13-BP OLIGONUCLEOTIDE CONTAINING E-BOX SEQUENCE
(Transcription factor 4)
referenceHorton et al. 'Nucleic 47 8375 2019
sourceHomo sapiens
experimentX-ray (resolution=1.49, R-factor=0.222)
structural superfamilyHLH, helix-loop-helix DNA-binding domain;
sequence familyHelixloophelix DNAbinding domain;
multimeric complexes6od3_ABH 6od3_EF 6od3_IJ 6od4_AB 6od5_AB 8osb_ABE
redundant complexes6od4_H 6od5_C 8osb
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNNRERR

Estimated binding specificities ?

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# IC=4.434 IC/col=0.739 n_of_columns=6 specificity:   
A |  16   0   0   0  24  54
C |  54   0   0   0  24  16
G |  13  96   0  96  24  13
T |  13   0  96   0  24  13
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updated Fri Sep 13 22:49:23 2024