interface graph thumbnail
legend  pdf

structure nameCASPOSASE BOUND TO INTEGRATION PRODUCT
(CRISPR-ASSOCIATED ENDONUCLEASE CAS1)
referenceHickman et al. Elife 9 ? 2020
sourceMETHANOSARCINA MAZEI
experimentX-ray (resolution=3.10, R-factor=0.200)
sequence familyProtein of unknown function DUF48;
multimeric complexes6opm_ABCD
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRFRRMS

Estimated binding specificities ?

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# IC=3.920 IC/col=0.560 n_of_columns=7 specificity:   
A |   0   9   4  96  24  24  19
C |  96   9  81   0  24  24  20
G |   0  67   7   0  24  24  19
T |   0  11   4   0  24  24  38
scan!

Dendrogram of similar interfaces ?

matrix format
  
  HA--------FAKA----WA------RC----------FCRGRG--TC--YT--LT--AT--------SAKCYCEARCLC--------VT----   L                   +---6opm_B    
                                                                                                       +---------------1 
  --DTVT----------STQTFT----------------------PT--STFT------------------------------TTKT--LTDT--       !               +---7cr6_D    
                                                                                                     --3 
  --HC----------DC----KTRTLT--NT--HCRC----------AT--YT--LTLCSTRTNTQTFTNC--SC----------------FTFT   L   !          +--------5xvp_B    
                                                                                                       +----------2 
  --HCVTETET--PG----EG----RT--RTET----ST----------STATST--------------KT--YT------ET----RT------                  +--------6kdv_A    
                                                                                                     

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updated Fri Sep 13 22:52:42 2024