5xvp_B : 3D-footprint complex

structure name	E. FAE CAS1-CAS2/PRESPACER/TARGET TERNARY COMPLEX REVEALING THE FULLY INTEGRATED STATES (CRISPR-ASSOCIATED ENDONUCLEASE CAS1)
reference	Nam et al. Nature 550 137 2017
source	ENTEROCOCCUS FAECALIS TX0027
experiment	X-ray (resolution=3.00, R-factor=0.196)
sequence family	Protein of unknown function DUF48 189;
multimeric complexes	5xvn_ABCDEF 5xvn_IJKLMN 5xvo_ACF 5xvo_BDE 5xvo_IJLMN 5xvp_ACEF 5xvp_BD
redundant complexes	5xvn_L 5xvo_J
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5xvp_B interface=70,71,72,146,150,153,174,178,182,184,185,189,206,207,208,209,215,237,245,248, mgwrtvvvnkhsklsyknnhlvfkaidhqelihlseidvlllettdislttmllkrlidekilvlfcddKRLpigkilpfygrhdsslqltrqlawteerkgqvwtaiiaqkitnqslhlaqrdygqkaaallamraelrlfdpaNregHaaRsyfntlfgndftreqendinAglnYgytLlLSifaRelvqtgcftqlglkhaNQFNdfnlaSdlmepfrplvdqiiyenrkeaFpimkrklFalFmntymykkkqmfltniatdytkhvvkvlnqeeegvpefgi
interface signature	KRLNHRAYLLSRNQFNSFFF

Estimated binding specificities ?

contact

# IC=9.811 IC/col=0.172 n_of_columns=57

specificity:

A |   4   8  16   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  84  92  24  24   0   4   0   0
C |   4  12  72  92  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   4   0  24  24  96   4  96   0
G |  84  60   4   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   4   4  24  24   0   4   0  96
T |   4  16   4   4  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   4   0  24  24   0  84   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --HC------------DC----KTRTLT----NTHCRC--AT--YT--LTLCSTRTNTQTFTNC--SCFT--FTFT   L               +----5xvp_B    
                                                                                     +-----------2 
  HA------------KA----WA--------RC--------TC--YT--LT--AT--------SAKCYC--VT----   L   !           ! +---6opm_B    
                                                                                   --3           +-1 
  --DTVT------ST----ST--FT--------------PT--STFT------------------------KTDT--       !             +---7cr6_D    
                                                                                     ! 
  --HCVTETETYT--PG----EG----RTYT------------STATST--------------KT--YT--------       +----------------6kdv_A

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updated Sun Aug 3 10:30:24 2025