structure name | CRYSTAL STRUCTURE OF THE HUMAN PAX-6 PAIRED DOMAIN-DNA COMPLEX REVEALS A GENERAL MODEL FOR PAX PROTEIN-DNA INTERACTIONS (HOMEOBOX PROTEIN PAX-6) |
reference | Epstein et al. 'Genes 13 1263 1999 |
source | Homo sapiens |
experiment | X-ray (resolution=2.50, R-factor=0.233) |
structural superfamily | Homeodomain-like; |
sequence family | 'Paired box' domain; |
links to other resources | NAKB PDIdb DNAproDB |
protein sequence | |
interface signature | NRSNCSKISRSVSSNRR |
Estimated binding specificities ?
readout + contact |
A | 96 2 0 16 59 24 24 32 3 4 1 4 C | 0 92 2 59 0 24 24 61 2 2 0 71 G | 0 2 93 12 12 24 24 1 91 2 93 2 T | 0 0 1 9 25 24 24 2 0 88 2 19scan! |
Dendrogram of similar interfaces ?
matrix formatHGSGRGHGRT--RT--STKGRGTTLGNT-------- L +-----------------------------1u78_A +-1 --------------RT----------ITQCNAACRG L +-2 +-----------------------------6a8r_A ! ! --------------------------VAQTNA---- L +-3 +-----------------------------1fjl_B ! ! ----------KG--RT----------IAQCNAYA-- L +-4 +-----------------------------1nk2_P ! ! ------------------------RTVAITNAMCRG L --5 +-----------------------------1yrn_A ! --------------------------VAQTNA---- L +-----------------------------5hod_A |
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updated Fri Sep 13 22:55:36 2024