interface graph thumbnail
legend  pdf

structure namePBX1, HOMEOBOX PROTEIN HOX-B1/DNA TERNARY COMPLEX
(PROTEIN HOMEOBOX PROTEIN HOX-B1)
referenceBatchelor et al. 'Cell(Cambridge,Mass.)' 96 587 1999
sourceHOMO SAPIENS
experimentX-ray (resolution=2.35, R-factor=0.243)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes1b72_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRIQNM

Estimated binding specificities ?

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# IC=4.822 IC/col=0.804 n_of_columns=6 specificity:   
A |   5  15  65   0   0  80
C |  81  21   5   0  96   6
G |   5  50   5   0   0   5
T |   5  10  21  96   0   5
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --RT--IAQCNA----MG----   L                         +---1b72_A    
                                            +--------2 
  --RTQTVAQTNA----------   L                !        !   +8osb_E    
                                       +----3        +---1 
  RART--VTKGNA------KA--   L           !    !            +2lkx_A    
                               +-------4    ! 
  ------NCIC--RGRG------   L   !       !    +------------4xrm_B    
                             --5       ! 
  --RC--IAQCNA----YC----   L   !       +-----------------3rkq_B    
                               ! 
  ----------------YCFAKC       +-------------------------6pe2_B

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updated Fri Sep 13 15:25:57 2024