| structure name | CRYSTAL STRUCTURE OF THE DNA BINDING DOMAINS OF HUMAN TRANSCRIPTION FACTOR ERG, HUMAN RUNX2 BOUND TO CORE BINDING FACTOR BETA (CBFB), IN COMPLEX WITH 16MER DNA CAGAGGATGTGGCTTC (TRANSCRIPTIONAL REGULATOR ERG) |
| reference | Tsodikov et al. Structure 29 404 2021 |
| source | HOMO SAPIENS |
| experiment | X-ray (resolution=4.25, R-factor=0.313) |
| structural superfamily | "Winged helix" DNA-binding domain; |
| sequence family | Etsdomain; |
| multimeric complexes | 6vge_AD 6vgg_AD |
| redundant complexes |  6vgg_A
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | KRRY |
Estimated binding specificities ?
| contact |  |
A | 13 54 0 0 0 0 C | 54 13 0 96 96 0 G | 16 13 0 0 0 0 T | 13 16 96 0 0 96scan! |
Dendrogram of similar interfaces ?
matrix format------DCKT--RGAT--RCYA------ L +---5e8i_D +---------------------6 ------EC----RG----RGYC------ L ! +---2stw_A ! --------KT--RGAT--RGYA------ L ! +1bc8_C +-17 +----------5 ------ECKT--RGAT--RGNT------ L ! ! ! +1pue_E ! ! +-----------8 ------------------RG--NG---- ! ! ! ! +7dci_A ! ! ! +-----------2 --------STVT------RGQTNTMT-- L ! +-14 +5d5v_B ! ! ------DCKT--RG----RGYA------ L ! ! +7jsa_J ! ! +-------------4 --------KT--RGSA--RGQA----RA L ! +-------10 +1yo5_C ! ! ------EAKT--RGAT--RGYA----RT L ! +--------------3jtg_A ! SG----DCKT--RG----RGYA------ L +-18 +------3zp5_A ! ! +-----7 --NC--------TT----CT--NGKG-- L ! ! ! +------7rh2_B ! ! +-----9 ------------TT----CT--NGKG-- L ! ! ! ! +7oot_B ! ! +-11 +------------3 ----------RTNT--RGSTAT--RT-- L ! ! ! ! +1t2k_B ! ! +--13 ! ------DCKT--RGST--RGYC------ L ! ! ! ! +------------------4uno_A ! ! +-15 ! ------DCKT--RGST--RGYA------ L -19 ! ! ! +--------------------4bnc_A ! ! ! ! --------KT--RG----RGYA------ L ! ! ! +------------------------4lg0_B ! +-16 ------ECKT--RGAT--RGHT----RA L ! ! +4mhg_A ! ! +--------------------1 --------KT--RG----RGYA------ L ! +--12 +4l18_B ! ! ----NTTCTA----------------RT L ! +--------------------5zux_A ! ----------NA----RAHT--STLT-- L +----------------------------2a07_J |
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updated Fri Dec 23 01:38:44 2022