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legend  pdf

structure nameCRYO-EM STRUCTURE OF HTLV-1 INSTASOME
experimentNMR
structural superfamilyRibonuclease H-like;DNA-binding domain of retroviral integrase;
sequence familyIntegrase core domain; Integrase DNA binding domain; Integrase Zinc binding domain;
multimeric complexes6voy_AD 6voy_BC
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureIRPTQRRLKW

Estimated binding specificities ?

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# IC=2.373 IC/col=0.396 n_of_columns=6 specificity:   
A |  74  24   0  21  13  14
C |   7  24   0  21  14  14
G |   7  24   0  33  13  52
T |   8  24  96  21  56  16
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----IT--RT----------PATA--QCRG--------RALAKA----------WA   L                             +6voy_C    
                                                                         +-----------------1 
  --------RT----------PATA--ECRG----TTHT------QA--ACAT--WA             +-4                 +6z2y_B    
                                                                       ! ! 
  ITLTRTPT----KT--HTETPAQA--EARC----PT--------KALTNT--VATA   L         ! +------------------3oym_A    
                                                                 +-----5 
  ----VT--PT----------PAQAAGEARCQG------------------------   L   !     !         +----------3jca_E    
                                                                 !     +---------3 
  --------QTDT--TA------QG--ECSCKG------------------------     --6               !         +6vdk_A    
                                                                 !               +---------2 
  ----------DT----------QG--ECSGHCQT----------------------       !                         +6rwm_A    
                                                                 ! 
  --------------------PAQGAGEARGQC------------------------       +--------------------------5m0q_A    
                                                               

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updated Tue Dec 19 15:27:18 2023