6xgw_A : 3D-footprint complex

structure name	ISCTH4 TRANSPOSASE, PRE-REACTION COMPLEX, PRC
reference	Kosek et al. 'Embo 40 e105666 2021
experiment	X-ray (resolution=3.50, R-factor=0.252)
structural superfamily	Ribonuclease H-like;
sequence family	Transposase, Mutator family; MULE transposase domain;
multimeric complexes	6xg8_AB 6xgw_AB
redundant complexes	6xg8
reference complex	6xg8_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6xgw_A interface=54,64,66,69,86,88,100,102,121,122,137,138,139,142,357,358,360, iitpekkelirnliseynitsakdlqealkdllgdtiqnmleaeldehlgyekYesteeaksnYrNgyTsktlkssvgqveidipRdRnaefepkivprYkRdiseienkiiamyargmsTReineqiqeiygfevSAEmvSkitdkilpeieewqkrplgevypivfidaihfsvkndgivgkkavyivlaidiegqkdvigiyvgenesskfwlsvlndlknrgvkdililcadalsgikdainaafpnteyqrcivhqirntlkyvsdkdrkefardlkriytapnekagydqmlevsekwekkypaamkswksnwdvicpffkyseelrkimyttntieslnssyrrinksrTVfPgdqsllksiylatvkitskwtmryknwglilgqlqimfegr
interface signature	YYNTRRYRTRSAESTVP

Estimated binding specificities ?

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# IC=17.196 IC/col=0.819 n_of_columns=21

specificity:

A |   2   0   0  82  85  88  24  24  24   4   0  24   2  24   0   0   2  96  92  96   8
C |   2   0   0   8  11   4  24  24  24  10   4  24   4  24   2   0  10   0   0   0  84
G |   4  96   0   2   0   2  24  24  24   5  90  24   2  24   2  96   2   0   2   0   2
T |  88   0  96   4   0   2  24  24  24  77   2  24  88  24  92   0  82   0   2   0   2

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Dendrogram of similar interfaces ?

matrix format

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updated Fri Jan 9 11:32:30 2026