6xgw_A : 3D-footprint complex

structure name	ISCTH4 TRANSPOSASE, PRE-REACTION COMPLEX, PRC
reference	Kosek et al. 'Embo 40 e105666 2021
experiment	X-ray (resolution=3.50, R-factor=0.252)
structural superfamily	Ribonuclease H-like;
sequence family	Transposase, Mutator family; MULE transposase domain;
multimeric complexes	6xg8_AB 6xgw_AB
redundant complexes	6xg8
reference complex	6xg8_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6xgw_A interface=54,64,66,69,86,88,100,102,121,122,137,138,139,142,357,358,360, iitpekkelirnliseynitsakdlqealkdllgdtiqnmleaeldehlgyekYesteeaksnYrNgyTsktlkssvgqveidipRdRnaefepkivprYkRdiseienkiiamyargmsTReineqiqeiygfevSAEmvSkitdkilpeieewqkrplgevypivfidaihfsvkndgivgkkavyivlaidiegqkdvigiyvgenesskfwlsvlndlknrgvkdililcadalsgikdainaafpnteyqrcivhqirntlkyvsdkdrkefardlkriytapnekagydqmlevsekwekkypaamkswksnwdvicpffkyseelrkimyttntieslnssyrrinksrTVfPgdqsllksiylatvkitskwtmryknwglilgqlqimfegr
interface signature	YYNTRRYRTRSAESTVP

Estimated binding specificities ?

readout + contact

# IC=17.369 IC/col=0.827 n_of_columns=21

specificity:

A |   0   0   0  70  87  92  24  24  24   2   0  24   0  24   0   0   2  96  94  87   2
C |   0   0   0  11   2   2  24  24  24  13   2  24   0  24   1   0  16   0   0   2  90
G |   0  96   0  15   2   2  24  24  24  14  90  24   2  24   2  96   2   0   2   2   4
T |  96   0  96   0   5   0  24  24  24  67   4  24  94  24  93   0  76   0   0   5   0

scan!

Dendrogram of similar interfaces ?

matrix format

home
updated Sat Aug 2 15:27:23 2025