3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

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updated Thu Jul 31 12:48:23 2025

structure name	ACTIVE STATE DOT1 BOUND TO THE UNACETYLATED H4 NUCLEOSOME
source	XENOPUS LAEVIS
experiment	NMR
structural superfamily	Histone-fold;lambda repressor-like DNA-binding domains;p53-like transcription factors;Nucleic acid-binding proteins;P-loop containing nucleoside triphosphate hydrolases;
reference complex	5o9g_F 6a5l_g 6ftx_B 6r8y_H 6x0n_f 7k6p_A 7k6p_D 7nkx_f 7u0g_M 7vdt_B 7xcr_F 7xzx_N 7xzz_N 8xgc_4
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7k6p_A interface=3,4,5,47, kpHRYrpgtvalreirryqkstellirklpfqrlvreiaqdfmtdlRfqssavmalqeaseaylvalfedtnlcaihakrvtimpkdiqlarrirger > 7k6p_B interface=30, krhrkvlrdniqgitkpairrlarrggvkRisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfg > 7k6p_C interface=31, akaktrssraglqfpvgrvhrllrkgnyaeRvgagapvylaavleyltaeilelagnaardnkktriiprhlqlavrndeelnkllgrvtiaqggvlpniqsvllpk > 7k6p_D interface=2, tRkesyaiyvykvlkqvhpdtgisskamsimnsfvndvferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtcytsa > 7k6p_E interface=1,26,44, RyrpgtvalreirryqkstellirkLpfqrlvreiaqdfmtdlRfqssavmalqeaseaylvalfedtnlcaihakrvtimpkdiqlarrirger > 7k6p_F interface= KrhrkvlrdniqgitkpairrlarrGgvkrisgliyeetrgvlKvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 7k6p_G interface= AkaktrssraglqfpvgrvhrllrkGnyaervgagapvylaavLeyltaeilelagnaardnkktriiprhlqlavrndeelnkllgrvtiaqggvlpniqsvllpk > 7k6p_H interface=2, tRkesyaiyvykvlkqvhpdtgisskamsimnsfvndvferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtcytsa