interface graph thumbnail
legend  pdf

structure nameTHE GLUCOCORTICOID RECEPTOR IN COMPLEX WITH FLUTICASONE FUROATE, A PGC1A COACTIVATOR FRAGMENT AND SGK 23BP
(Glucocorticoid receptor)
referenceWissler et al. Nat.Struct.Mol.Biol. 30 286 2023
sourceHomo sapiens
experimentX-ray (resolution=2.70, R-factor=0.216)
structural superfamilyNuclear receptor ligand-binding domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyLigandbinding domain of nuclear hormon; Zinc finger, C4 type two domains;
multimeric complexes7prv_AB 7prw_AB
reference complex7prw_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVR

Estimated binding specificities ?

contactlogo
# IC=4.087 IC/col=0.681 n_of_columns=6 specificity:   
A |   0   0  11  24   9  19
C |   0   0   9  24  67   9
G |   0  96   0  24   9  11
T |  96   0  76  24  11  57
scan!

home
updated Fri Jan 9 16:51:59 2026