interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF SCINO2P-SCINO4P BOUND PROMOTER DNA
referenceKhan et al. 'Int 23 ? 2022
experimentX-ray (resolution=2.25, R-factor=0.215)
structural superfamilyHLH, helix-loop-helix DNA-binding domain;
sequence familyHelixloophelix DNAbinding domain;
multimeric complexes7xq5_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHERRR

Estimated binding specificities ?

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# IC=3.705 IC/col=0.463 n_of_columns=8 specificity:   
A |   6   0  75  24   6  24  24  68
C |   9  96   6  24   6  24  24   9
G |  75   0   9  24  78  24  24  13
T |   6   0   6  24   6  24  24   6
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RT----NTRGECRCQT           +-----------------------------2ypa_A    
                           +-1 
  ------NT--ETRCMT       +-2 +-----------------------------2ql2_D    
                         ! ! 
  NTRGEC--RC------     --3 +-----------------------------2ql2_A    
                         ! 
  NG--ECRGRC------   L   +-----------------------------6od3_F    
                       

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updated Wed Dec 18 14:11:29 2024