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legend  pdf

structure nameSTRUCTURE OF THE SCL:E47:LMO2:LDB1 COMPLEX BOUND TO DNA
(T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1)
referenceHoosdally et al. 'Cell 4 135 2013
sourceHOMO SAPIENS
experimentX-ray (resolution=2.80, R-factor=0.226)
structural superfamilyHLH, helix-loop-helix DNA-binding domain;
sequence familyHelixloophelix DNAbinding domain;
multimeric complexes2ypa_AB 2ypb_AB
redundant complexes2ypb_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: LDB1
CAGGTGPubMed2ypa_AB(6.64e-03)
CANNTGPubMed2ypa_AB(6.64e-03), 2ypb_AB(1.02e-02)
CAGCTGPubMed2ypa_AB(6.64e-03)
term: LMO2
CANNTGPubMed2ypa_AB(6.64e-03), 2ypb_AB(1.02e-02)
CAGGTGPubMed2ypa_AB(6.64e-03)
CAGATGPubMed2ypa_AB(6.64e-03), 2ypb_AB(3.89e-05)
CAGCTGPubMed2ypa_AB(6.64e-03)

Dendrogram of similar interfaces ?

matrix format
  
  --HGNT--ECRCRG   L                  +----------------7d8t_A    
                         +------------1 
  --HGNTMTEARCRG       +-2            +----------------1nlw_D    
                       ! ! 
  --HG----ETRTRG     --3 +-----------------------------5v0l_A    
                       ! 
  NG--RG--------   L   +-----------------------------6od3_F    
                     

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updated Fri Sep 13 16:50:50 2024