interface graph thumbnail
legend  pdf

structure nameSTRUCTURE AND FUNCTION OF THE B/HLH/Z DOMAIN OF USF
(PROTEIN UPSTREAM STIMULATORY FACTOR)
reference'EMBO 13 180 1994
sourceHomo sapiens
experimentX-ray (resolution=2.90, R-factor=?)
structural superfamilyHLH, helix-loop-helix DNA-binding domain;
sequence familyHelixloophelix DNAbinding domain;
multimeric complexes1an4_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQVERRQ

Estimated binding specificities ?

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# IC=4.250 IC/col=0.708 n_of_columns=6 specificity:   
A |  12   0   0  96  24  12
C |  12   0   0   0  24  60
G |  60  12  96   0  24  12
T |  12  84   0   0  24  12
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: USF
CACGTGPubMed1an4_AB(1.12e-07)
CACATGPubMed1an4_AB(1.42e-03)
CACGTGACPubMed1an4_A(6.42e-03), 1an4_AB(7.20e-08)
CATGTGPubMed1an4_AB(1.42e-03)

Dendrogram of similar interfaces ?

matrix format
  
  RTECRGRC------   L       +-----------------------------6od3_F    
                         +-1 
  --HGNT--ET--RG   L   +-2 +-----------------------------6g1l_A    
                       ! ! 
  --HG--ITECRCRG   L --3 +-----------------------------5nj8_D    
                       ! 
  ----NT--ETRCMT       +-----------------------------2ql2_D    
                     

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updated Fri Sep 13 15:23:17 2024