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structure nameCRYSTAL STRUCTURE OF THE COBALT-ACTIVATED DIPHTHERIA TOXIN REPRESSOR- DNA COMPLEX REVEALS A METAL BINDING SH-LIKE DOMAIN
(DIPHTHERIA TOXIN REPRESSOR)
referenceHolmes et al. J.Mol.Biol. 292 653 1999
sourceCorynebacterium diphtheriae
experimentX-ray (resolution=3.20, R-factor=0.249)
structural superfamilyIron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;C-terminal domain of transcriptional repressors;
sequence familyIron dependent repressor, metal bindin; Iron dependent repressor, Nterminal D; MarR family;
multimeric complexes1c0w_ABCD 1ddn_ABCD
reference complex1ddn_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSPTSQ

Estimated binding specificities ?

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# IC=4.250 IC/col=0.850 n_of_columns=5 specificity:   
A |  12  12  96  12   0
C |  12  12   0   0   0
G |  12  12   0  84  96
T |  60  60   0   0   0
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updated Sat Aug 2 00:45:54 2025