1dct_B : 3D-footprint complex

structure name	DNA (CYTOSINE-5) METHYLASE FROM HAEIII COVALENTLY BOUND TO DNA (PROTEIN MODIFICATION METHYLASE HAEIII)
reference	Reinisch et al.
source	HAEMOPHILUS INFLUENZAE BIOTYPE AEGYPTIUS
experiment	X-ray (resolution=2.80, R-factor=0.226)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
sequence family	C5 cytosinespecific DNA methylase;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1dct_B interface=76,219,220,221,225,227,239,243,244, mnlislfsgaggldlgfqkagfriicaneydksiwktyesnhsaklikgdiskissdefpkcdgiiggppcqswsEggslrgiddprgklfyeyirilkqkkpifflaenvkgmmaqrhnkavqefiqefdnagydvhiillnandygvaqdrkrvfyigfrkelninylppiphlikptfkdviwdlkdnpipaldknktngnkciypnheyfigsySTIfmsRnRvrqwnepaftvQasgRQcqlhpqapvmlkvsknlnkfvegkehlyrrltvrecarvqgfpddfifhyeslndgykmignavpvnlayeiaktiksal
interface signature	ESTIRRQRQ

Estimated binding specificities ?

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# IC=5.938 IC/col=1.188 n_of_columns=5

specificity:

A |   0   0   0   0   7
C |   0   0   0  96   7
G |   0  96  96   0   7
T |  96   0   0   0  75

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ------EG------------------SGTGIGRGRGQC--RGQG--   L                      +-------1dct_B    
                                                             +------------1 
  ----CCITSG--------ECNCRCRC--------RGSGYC----NC   L   +-----2            +-------2c7p_A    
                                                       !     ! 
  ----------MGRGFGNG----------------------------   L --3     +--------------------4da4_B    
                                                       ! 
  NAFA------------------------------------------       +--------------------------2y7h_B

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updated Tue Dec 19 05:31:07 2023